Figure bending / rotation all out of sorts

Paradigm

Hi all,

I've posted about this before but have not ever gotten a satisfactory answer. Occasionally I will have a scene that I spend a long time in over several days and sometimes a figure will get all out of sorts. When I use a bend dial on a leg, for example, it will skew off to an odd angle rather than it's usual / predictable direction. If I apply a pose it will be out of sync and rotating the body or hip will produce unexpected angles and sometimes pop to different directions.

I've tried resetting the rigging, zeroing the pose and restoring the memorized pose. Importing a new figure and setting it up "fixes" the issue in that I can just delete the one that was all jacked-up, but it's a PITA and doesn't actually tell me what is wrong, so I do not accept "load a new figure" as a valid answer to my issue.